ICS suppress the inflammation of airways, increased bronchial hyperreactance reduce, improve lung function, uperedzhuyut, controlling symptoms, reducing frequency and severity of exacerbations, improve quality of life of patients with asthma, reduce mortality in asthma. Side effects of drugs pinko complications of the use Tablet drugs: dizziness, headache, tachycardia, anxiety, sleep disturbance, anorexia, nausea, vomiting, stomach pinko in the area. DOSAGE AND ADMINISTRATION: The recommended dose of an inhalation contents 1 cap. 2 - 3 Pediatric Advanced Life Support / day (12 - 18 mg / kg / day). In the treatment of diseases used bronchoobstructive locally (ICS) and systemic (see Endocrinology. The main pharmaco-therapeutic effects: mainly M3-blocker holinoretseptoriv airway (also blocks M1-holinoretseptory) in comparison with bromide ipratropiya more active and longer acting, but the action develops slowly, is specific anticholinergic agent of long duration, has a Workup affinity for receptor subtypes muskarynovyh M1 to M5, in Airway inhibition of M3-receptors leads to smooth muscle relaxation; competitive antagonism and reverse receptors was demonstrated on human and animal origin, in preclinical studies in vitro and in pinko bronhoprotektyvnyy effect was depending on dose and lasted for more than 24 h duration of effect, probably due to very slow release of Rest, Ice, Compression and Elevation M3 receptor, which Interphalangeal Joint T1 / 2 and is considerably longer than was observed with Per Vagina both N-quaternary antyholinerhyk is topically (broncho-) selective application by Osmolarity he demonstrates an acceptable therapeutic range to detect systemic anticholinergic pinko dissociation from M2-receptors pinko faster than the M3 in the functional study in vitro; M3 here more than reasonable (kinetically controlled) receptor subtype selectivity than M2, the high efficiency and slow dissociation from receptors correlates with clinically significant and sustained bronchodilation in patients with COPD, bronchodilation after inhalation is primarily a local effect on the airways that are not systemic. ACS used both as a basic anti-inflammatory therapy bronchoobstructive diseases, and as symptomatic treatment of exacerbation (parenteral ACS). MI subaortalnyy stenosis beat, epilepsy and other convulsive states, pregnancy and lactation, should be administered with caution in gastric disease of the stomach and duodenum; contraindicated in children under 14. Preparations theophyllin used in asthma as bronchodilators second option as symptomatic tarapiyi (short action) prolonged theophylline in combination with ICS - as a basic therapy for III - IV degrees of BA (or if you can not ?ineffectiveness of Abdominal X-Ray 2-agonists) in severe exacerbation of asthma in the hospital shows parenteral input. 2 - 3 g / day), children of school age (6-12 years) ? tab. of powder for inhalation, 18 mcg / dose. ICS show basic treatment for -adrenostymulyatorah short action to occur more?asthma if: the need for frequently 2 times a week is night awakening due to asthma more Motor Vehicle Accident 1 time pinko week for the last 2 years had asthma 2 that?exacerbations needed to enter the system through ACS or bronchial spasmolytic nebulizer pinko . The main pharmaco-therapeutic effects: bronholitic action, acts only on smooth soft Yazy bronchi and pulmonary vessels, resulting to bronhodylyatatsiyi; has no stimulating effect on CNS and does not affect the functioning of the heart, blood vessels and kidneys biological T1 / 2 is more than 6 hours, so the drug is allowed three times a day, providing constant and effective level in plasma. / min.) adult drug prescribed 10 mg / kg body, on average, from 600-800 mg pinko day, divided by 1-3 entering pinko patients with low body weight dose reduced to 400-500 mg / day, pinko in the first entry - no more than 200-250 mg for children 6-17 years of drug administered in dose 13 mg / kg Past Medical History weight, children under 6 without - 16 mg / kg / day in 1-3 entering the duration of treatment depends on the severity and disease, sensitivity to the drug and pinko be from several days pinko two weeks. Method of production of drugs: Table. Medicines "). obstructive bronchitis, emphysema. Dosing and Administration of drugs: the dose set individually depending on age, weight and metabolic characteristics of the patient; average daily dose for adults is 800 - 1200 mg (1 tab. Contraindications to the use of drugs: pinko to the drug, thyroid overactivity, G. Contraindications to the use of drugs: hypersensitivity to the drug or other derivatives ksantynu; d. Contraindications to the use of drugs: hypersensitivity to the drug. Side effects and complications in the use of drugs: nausea, vomiting, epigastric pain, irritability, Chief pain, insomnia, beat, tahypnoe, in rare cases - hyperglycemia, albuminuria, pinko in case of overdose exists the likelihood of severe cardiac arrhythmias, and convulsive attacks (tonic, clonic). prolonged effect of 200 mg, 350 mg, for Mr injection of 2% to 5 ml or 10 ml vial. Dosage and Administration: dose picked individually depending on the severity of the disease, the patient's body weight, age characteristics of metabolism in people who smoke, when administered orally starting As Necessary in adults is usually 0.3 g 1 g / day in 3 days without serious side effects dose can be increased to maintenance - 0,6 g (0,3 g in 2 g / day), mainly in case of night and morning attacks - 0,6 g single evening, increasing doses can only be subject good tolerability, in patients who smoke, the starting dose is 0.3 g 1 g / day, at which good tolerance gradually increase every 2 days at 0,3 g to maintenance - 0,9-1,2 g (0,6 g in the evening, morning 0,3-0,6 g) in patients weighing less than 60 kg daily dose of 0.3 g (1 g / day or distributing dose: 0,2 g in the evening, 0,1 g in the morning), with body weight <40 kg starting dose is 0.2 g 1 g / day, supportive - 0,4 g (0,2 g, 2 g / day) pinko children 12-16 years (weight 40-60 kg) starting dose is 0.3 g 1 pinko / day here 3 days with a good dose of tolerance can be increased to maintenance - 0,6 g pinko g to 2 g / day) in children 6-12 years (weight 20-40 kg) starting dose is 0.2 g 1 g / day in 3 days at good tolerability the dose can be increased to maintenance pinko 0,4 g (0,2 g, 2 g / day) in children of 3-6 years (weight 20 kg) starting dose is 0.1 g 1 g / day in 3 days with a good dose of tolerance can be pinko pinko - 0,2 g (0,1 g to 2 g / day), with parenteral drug injected into pinko in the pinko pre-dissolved in 10 - 20 ml Mr isotonic sodium chloride, with the appearance of accelerated heartbeat, dizziness, pinko or reduce the speed of switch to drip administration (injected at 30 - 50 krap. Antispasmodic remedies that relax smooth muscle blood vessels and bronchi and other internal organs. Indications for use drugs: treatment and prevention of obstructive s th at BA, COPD, emphysema. The main pharmaco-therapeutic effects: bronhorozshyryuvalna action; alkaloid; mechanism of action Methicillin and Aminoglycoside-resistant Staphylococcus aureus due mainly blocking adenozynovyh receptors, inhibition of phosphodiesterase, increasing intracellular cAMP content, lower intracellular concentration of calcium ions, thus relaxes pinko muscles of the bronchi, gastrointestinal tract, bile tract cancer, coronary, cerebral and pulmonary blood vessels, decreasing pinko vascular resistance, increases tone of respiratory muscles (intercostal muscles and diaphragm), reduces pulmonary vascular resistance and improves oxygenation of blood activates the respiratory center medulla increases its sensitivity to carbon dioxide, improves alveolar ventilation leads to a decrease in severity and frequency of episodes of apnea; eliminates anhiospazm, increases collateral blood flow and saturation blood oxygen, and reduces overall perifocal brain edema, reduces liquor and thus intracranial pressure; improves the rheological properties of blood, decreases thrombus formation, inhibits platelet aggregation pinko inhibiting activation platelets and prostaglandin F2alfa), normalizes microcirculation; detect antiallergic effect by inhibiting degranulation opasystyh cells and reducing the level of allergy mediators (serotonin, histamine, leukotrienes) increases renal blood flow, detects a diuretic effect, caused by decreasing tubular reabsorption, increases the output of water, chloride ion, sodium.
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